There are Defender settings in the GPO that are detected as threats. These are settings that disable modules, creating a vulnerability.
If such settings are set, they will be detected as threats "VirTool:Win32/DefenderTamperingRestore" and the event type Alert with event ID 1116 is raised.

If you must disable modules, you must define the threat as an exception so that it is ignored when it is detected.

Proceed as follows:
1. Double-click Defender Management > Configuration Profiles > Default Defender to open the settings.

2. Navigate to Actions for threats and add the threat name and ID using the plus sign under Threat action. Use the drop-down menu under Actions to decide what to do with the threat. It is recommended that you ignore the threat.

This will cause the threat to be ignored and removed from the event list.